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Benign symmetric lipomatosis (also known as Benign symmetric lipomatosis of Launois–Bensaude, Madelung's disease, multiple symmetric lipomatosis and cephalothoracic lipodystrophy) is a cutaneous condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. The German surgeon Otto Wilhelm Madelung was the first to give a detailed description of the disorder. This condition is very rare with an estimated incidence rate of 1 in 25,000 and affects males up to 30 times more frequently than females. The cause of the disease remains unknown, but there is a strong correlation with alcohol abuse; abstinence from alcohol prevents disease progression. Defects in the adrenergic-stimulated lipolysis and accumulation of embryological brown fat has also been reported. Cosmetic disfigurement due to the fat deposition in the cervicothoracic region results in a 'pseudoathletic appearance'. This resembles the Italian statue Warrior of Capestrano and carvings of Queen of Punt (Egypt). Traditionally the treatment is mainly surgical, consisting of the removal of the lipomas, although recent study has proposed liposuction and phosphatidylcholine injection as possible alternatives. == See also == * Lipomatosis * List of cutaneous conditions * Madelung's deformity 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Benign symmetric lipomatosis」の詳細全文を読む スポンサード リンク
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